While a robust body of work exists documenting widening rural-urban disparities in longevity, relatively little research has focused on heterogeneity in these trends, specifically with regards to racial and regional differences. Using restricted mortality data from the National Vital Statistics System from 1995-2019, we document trends in rural-urban life expectancy by racial and regional group. The results indicate that rural-urban differences in life expectancy over time are dynamic, diverging for some places and converging for others. For example, we find a robust rural longevity disadvantage for all racialized populations residing in the South and for the white population across all regions. A rural longevity advantage, however, is revealed for Black populations in the Midwest and West, and Hispanic populations in the Midwest and Northeast, indicating there is substantial heterogeneity in the rural-urban life expectancy gap based on spatial context and racial group.Decomposition results show that both regional and rural-urban life expectancy gaps are largely attributable to differences in age-at-death from chronic illnesses among most racialized groups. These shifting demographic components will require place-based approaches to minimize inequality in longevity patterns across regions. In particular, the results signal the need for greater investment in health promoting resources in regions and among populations of greatest need.